When compared to the JT IMRT and SJ IMRT plans, FJ IMRT plan led to a statistically significant improvement in the NTCP and low-middle dosimetric parameters of the lung, and the improvement had a moderately positive correlation with the length of PTV-C inferior, with a correlation coefficient ranging from 0.523 to 0.797 the FJ IMRT plan exhibited better lung sparing in low-dose volumes than the JT VMAT plan.
The homogeneity and conformity of the target in the four plans were basically equivalent. The correlation between the length of PTV-C below the upper boundary of lung tissue (PTV-C inferior) and dosimetric parameters and NTCP of the lung tissue were analyzed. Dosimetric parameters, tumor control probability (TCP) and normal tissue complication probability (NTCP), monitor units (MUs), delivery time and gamma passing rate, as a measure of dosimetric verification, were compared. MethodsįJ IMRT plans were generated for thirty-five patients and compared with jaw tracking (JT) IMRT, static jaw (SJ) IMRT and JT volumetric modulated arc therapy (VMAT). To evaluate the dosimetric and biological benefits of the fixed-jaw (FJ) intensity-modulated radiation therapy (IMRT) technique for patients with T-shaped esophageal cancer.